The Cause of Cataracts P.8






(4) How does the PRESSURE work on the      lens?



7. The progression of wedge-shaped


<Opaque lines>


<Wedge-shaped opacity grows toward
    the pole.>


8. Speckled opaqueness


9. The Breakdown of the human lens


10. Subcapsular cataract is also caused
  by the PRESSURE.


11. Miotics-induced cataract


12. Christmas tree cataracts

7.  The progression of wedge-shaped cataracts


Insoluble proteins and insoluble aggregates will adhere to the surface of the cell membrane around the water cleft. I think that as adhered insoluble substances stiffen the membrane of the fiber cell, the cell becomes more easily crushed by the PRESSURE. The insoluble substances adhere not only to the cell around the water cleft, but also to cells further from the equator.

Edward Cotlier writes as follows. gThe spaces between the lens fibersthe extracellular spaces of the lensare very small, accounting for only about 5% of the lens volume.19h It is conceivable that those insoluble substances adhere through these spaces to the surfaces of far cells.


<Opaque lines>

In the lens cortex away from the equator, very fine opaque lines of a large number come out in parallel, crossing the wedge-shaped opacity. It is conceivable that these lines of opaque substances are made from cells crushed by Pressure[b]1. Pressure[b]1 makes gaps in the layer of fiber cells. Consequently, the interceller connection of the neighboring layer breaks and the cell membrane is injured. I think, as if this power by the lump of wedge-shaped opacity would have rolled the crossing fiber cells in neighboring bundles, this power crushes the fiber cells and then makes opaque parallel lines.


<Wedge-shaped opacity grows toward the pole.>

When the wedge-shaped opacity has already developed, it is conceivable that besides Pressure[b]1, Pressure[b]2 also works. The latter is the power which drives the apex of the wedge-shaped opaque substance into an inter-layer space of bundles. This power, at the apex, expands the space between the layers. Consequently, as the opaque substances can pass easily through this space, the wedge-shaped opacity will grow rapidly toward the pole.


When the wedge-shaped opacity has increased to a certain degree, the PRESSURE spreads in every direction over the lens. This is because hardened opacity which receives the pressure has been made everywhere. As a result, the various ways of destroying the lens complicate the cataract. Depending on the progression of the cataract, the structure of the whole lens becomes weak. The lens will become more easily destroyed.


8. Speckled opaqueness


When wedge-shaped opacity has developed to a certain degree, speckled opaqueness comes out near the anterior pole of the lens cortex. Like the wedge-shaped opacity, it makes a plane parallel to the lens surface. When wedge-shaped opacity has developed to a certain degree, the epithelial cells in other than the equator are sandwiched between the capsule and the opacity.  Those epithelial cells will be crushed by this sandwiching power. This power is Pressure [d].

Moses describes, gIn the eye during accommodation,h and continues as follows. g3. The anterior surface of the lens becomes more convex. The posterior surface increases its curvature slightly.  4. Since the posterior pole remains fixed and the anterior pole moves forward, the thickness of the lens at the center increases.6h

In accommodation, although the anterior surface of the lens more expands than the posterior surface, the anterior capsule margin of expansion is less than the posterior margin. The diagram, in Fig.4-17 by Moses, shows the shape of the capsule. Accordingly, it is assumed that in accommodation, the anterior capsule puts stronger pressure on lens epithelial cells than the posterior capsule does on fiber cells. But in fact, it is thought that as the capsule presses the lens equator, the anterior polar portion of the lens cortex is pushed onto the anterior capsule. Pressure [d] is caused by Pressure[a] and Pressure[b]. Epithelial cells are sandwiched in that location.

Fig.4-17 The shape of the capsule by Robert A. Moses6

9.  The Breakdown of the human lens


The diagram of the prevalence of cataracts shows a rapid increase in cataracts from the age of about 50. (Fig.4-18) This is an unexpected incident for the plan of the human eye. For the plan, it was not anticipated that the UNREASONABLE POWER is used at that age. The occurrence of the collapse of fiber cells was not anticipated. This suggests that the planned life span of the human eye might be about 50 years.


Fig.4-18 The prevalence of cataracts by John Harding3



It is conceivable that after the opaqueness has advanced to near the anterior polar area of the cortex, lysosomal enzymes come to play a main role in the crushing the cell. The PRESSURE also continues working all over the lens until the later stage of cataracts. In this circumstance, as the capsule continues shaking the lens, cataract advances more steadily because of lysosomal enzymes. Then the wedge-shaped cataract develops gradually into a mature cataract : a gcataract in which the lens is completely opaque,1h then into a hypermature cataract : a gcataract in which the contents have become either solid and shrunken or soft and liquid,1h further into a morgagnian cataract : a gcataract with a fluid cortex and a hard nucleus1h and ultimately to phacolysis : gdissolution of the lens.1h It is the end form of age-related cataracts. The phacolysis causes phacolytic glaucoma: gglaucoma secondary to leakage of lens protein into the aqueous from a hypermature cataract.1h This is an extra.


10. Subcapsular cataract is also caused by the PRESSURE.


Cogan writes as follows. gUnderlying the pathogenesis of posterior cortical cataracts is the antecedent migration of epithelial cells beneath the posterior capsule from the equator toward the posterior pole.4h The cells in subcapsular cataracts are the very cells in wedge-shaped cataracts.

It is conceivable that in accommodation, a lifting power, or Pressure [c] works at the posterior polar region. The posterior capsule will be peeled off from the lens cortex and into this space, separated epithelial cells from the equator migrate.


11. Miotics-induced cataract


 This is a cataract caused by the application of miotics for a long period of time. gMioticsh are eye lotions which contract the pupil. The opaqueness of this cataract comes out under the anterior capsule as speckles.

    In miotics-induced cataracts, the PRESSURE works for a long time continuously on the equator. It will pass through the cortex to the anterior pole, and presses on epithelial cells in the anterior polar region. This Pressure [d] as repulsion for Pressure[a] and Pressure[b] crushes epithelial cells in the region.


12. Christmastree cataracts


In this rare cataract, brilliances like Christmas tree lights emerge in the lens nucleus. It is conceivable that the brilliance of this cataract is cholesterol in the cracks of the lens nucleus. I consider that the cracks are caused by the PRESSURE, and that the power is so strong as to crack a considerably hardened nucleus.

The Cause of Cataracts P.8